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. 2014 Sep 8;9(9):e106837. doi: 10.1371/journal.pone.0106837

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© 2014 Le et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A: Iba1 staining (red) of CA1 at normal young adult rat. B: the merged panel of Iba1 staining (red) and Dapi (blue) of CA1 at normal young adult rat. C: Iba1 staining (red) of CA1 at young adult rat 1d after surgery. D: the merged panel of Iba1 staining (red) and Dapi (blue) of CA1 at young adult rat 1d after surgery. E: Iba1 staining (red) of CA1 at normal aged rats. F: the merged panel of Iba1 staining (red) and Dapi (blue) of CA1 at normal aged rats. G: Iba1 staining (red) of CA1 at aged rat 1d after surgery. Activated microglia (white arrow) was observed. H: the merged panel of Iba1 staining (red) and Dapi (blue) of CA1 at aged rat 1d after surgery. I: western blot of TNF-α at hippocampus. J: western blot of IL-1β at hippocampus. Data were mean ± SD. *p<0.05 vs control. Bar = 50 um.