Table 2. Differentially-expressed miRNAs in Atypical coronary artery disease (ACAD) serum samples compared to control samples in training set and validation seta.
Training set | Validation set | |||||
miRNA | Control | ACAD | P valueb | Control | ACAD | P valueb |
(n = 10) | (n = 30) | (n = 34) | (n = 92) | |||
miR-487a | 184.27±23.54 | 400.95±41.28 | 0.002 | 251.31±23.03 | 460.59±37.71 | 0.027 |
miR-29b | 2290.91±410.84 | 635.31±145.71 | <0.001 | 1890.08±251.39 | 520.97±42.02 | <0.001 |
miR-502 | 1229.97±232.18 | 3186.68±368.78 | <0.001 | 1116.99±102.41 | 2772.15±412.40 | 0.016 |
miR-208 | 1551.19±167.21 | 3839.48±452.85 | <0.001 | 2051.02±330.05 | 5574.02±293.53 | <0.001 |
miR-215 | 86.76±24.00 | 385.73±37.45 | <0.001 | 198.80±23.97 | 418.96±28.89 | <0.001 |
The absolute concentrations of miRNAs are presented as mean ± SEM (fM/L).
Mann-Whitney unpaired test for rank sum.