Table 5. The two most significantly enriched pathways and the involved differentially expressed genes (DEG).
Biosynthesis of unsaturated fatty acids | Glycerolipid metabolism | ||
DEGsa | log2-Ratio (deformed/normal) | DEGs | log2-Ratio (deformed/normal) |
SCD5 | 1.41 | LPL | 10.25 |
GLG1 | −1.01 | PNPLA2 | 8.54 |
ELOVL6 | −1.08 | PPAP2A | 7.96 |
FAD | −1.19 | PPAP2B | 2.06 |
PTPLB | −1.20 | AGPAT6 | 1.46 |
ACAA1 | −1.35 | SHROOM3 | 1.18 |
PECR | −1.43 | ALDH7A1 | −1.06 |
MFSD4 | −1.54 | AKR1B10 | −1.14 |
DLEC1 | −1.87 | DGKD | −1.20 |
PTPLAD1 | −1.92 | GK5 | −1.23 |
HSDL1 | −2.31 | GLA | −1.26 |
LOC423119 | −3.37 | MOGAT1 | −1.28 |
AR | −3.01 | ||
LIPG | −3.01 |
SCD5 = stearoyl-CoA desaturase 5; GLG1 = golgi glycoprotein 1; ELOVL6 = ELOVL family member 6; PTPLB = protein tyrosine phosphatase-like B; ACAA1 = acetyl-CoA acyltransferase 1; PECR = privacy and electronic communications regulations; MFSD4 = major facilitator superfamily domain containing 4; DLEC1 = deleted in lung and esophageal cancer 1; PTPLAD1 = protein tyrosine phosphatase-like A domain containing 1; HSDL1 = hydroxysteroid dehydrogenase like gene; LOC423119 = Gallus gallus fatty acid desaturase 1-like; LPL = lipoprotein lipase; PNPLA2 = patatin-like phospholipase domain containing 2; PPAP2A = phosphatidic acid phosphatase 2A; PPAP2B = phosphatidic acid phosphatase 2B; AGPAT6 = 1-acylglycerol-3-phosphate O-acyltransferase 6; SHROOM3 = shroom family member 3; ALDH7A1 = aldehyde dehydrogenase 7 family, member A1; AKR1B10 = aldo-keto reductase family 1, member B10; DGKD = diacylglycerol kinase; GK5 = glycerol kinase 5; GLA = galactosidase, alpha; MOGAT1 = monoacylglycerol O-acyltransferase 1; AR = androgen receptor; LIPG = endothelial lipase.