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. 2014 Sep 8;9(9):e107188. doi: 10.1371/journal.pone.0107188

Figure 2. IL-1 signaling limits lung inflammation during B. pertussis infection.

Figure 2

Groups of four mice were either (A–D) uninfected or inoculated with B. pertussis and euthanized at (E–H) 7 days or (I–L) 28 days post-inoculation. Automated H&E staining was performed on 5 µm paraffin-embedded sections. Images were taken and are representative of 10–12 fields per group. Lung homogenate cytokine measurements (M–N) were measured by ELISA from uninfected mice or on days 3, 7, 14, or 28 post-inoculation (n = 4–8). ELISA significance was determined by one-way ANOVA with Dunnet’s post-hoc test. *p<0.05 represents a significant difference from WT mice.