TABLE 3.

Gag-specific CTLs at 16 to 20 weeks postinfection

Animal	Group	Wk assayed	Effector cell stimulation	% 51Cr released by target cells infected with vaccinia virusa
				Wild type	Expressing SIV Gag
182	Untreated	19	ConA	0	32
			SIV Gag	6	45
			SIV Gag 2	15	63
		16	ConA	23	77
			SIV Gag	14	73
200	Normal Ig	18	ConA	20	35
			SIV Gag	25	46
			SIV Gag 2	18	39
		20	ConA	14	24
			SIV Gag	37	38
			SIV Gag 2	13	50
186	Normal Ig	18	ConA	4	12
			SIV Gag	5	7
			SIV Gag 2	3	24
		20	ConA	0	5
			SIV Gag	6	12
			SIV Gag 2	12	37
176	SIVIG	19	ConA	2	24
			SIV Gag	12	20
			SIV Gag 2	20	40
191	SIVIG	16	ConA	22	18
			SIV Gag	16	36
		19	ConA	26	21
			SIV Gag	17	16
			SIV Gag 2	11	18

^aEffector cells were stimulated with concanavalin A (ConA) or once (SIV Gag) or twice (SIV Gag 2) with fixed peripheral blood lymphocytes infected with vaccinia virus expressing SIV Gag prior to the ⁵¹Cr release assay at an effector-to-target ratio of 10:1. Numbers in bold are significant.