TABLE 1.

Pulmonary histopathology following RSV challenge^a

Animal group	Pathology
	Bronchitis	Peribronchiolitis	Alveolitis
Vaccinated
Expt 1	0.5 ± 0.9	0.6 ± 0.4	0.3 ± 0.4
Expt 2	0.8 ± 0.4	1.4 ± 0.2	1.3 ± 0.4
Control
Expt 1	0.9 ± 0.5	1.1 ± 0.7	0.9 ± 0.8
Expt 2	0.6 ± 0.4	0.7 ± 0.3	0.3 ± 0.3

^aIn two separate experiments, lungs were harvested from vaccinated (rSV RSVG) or control (inoculated with PBS [Expt 1] or SV [Expt 2]) rats on the fifth day after RSV challenge. RSV challenge was performed approximately 4 weeks after immunization or control inoculation. Mean scores and standard deviation obtained from each group (n = 5) of rats are shown. Results show that previous vaccination does not result in excess inflammation following RSV challenge compared to that of control animals.