Table 3. Association between copy number of the GSTM1 gene and risk of prostate cancer according to smoking, alcohol consumption, body mass index and family history of prostate cancer.
| GSTM1 Copy Number | Ptrend | Pinteraction | ||||||
| 0 | 1 | ≥2 | ||||||
| Cases/Controls | ORa (CI95%) | Cases/Controls | ORa (CI95%) | Cases/Controls | ORa (CI95%) | |||
| Smoking | ||||||||
| Never | 98/114 | 1.0 | 200/173 | 1.11 (0.73–1.68) | 90/96 | 1.36 (0.95–1.95) | 0.58 | 0.71 |
| Former or Current | 61/80 | 1.0 | 113/103 | 1.31 (0.77–2.26) | 61/53 | 1.26 (0.79–2.02) | 0.30 | |
| Alcohol | ||||||||
| Never | 24/29 | 1.0 | 42/47 | 0.98 (0.40–2.38) | 18/21 | 0.94 (0.45–1.95) | 0.95 | 0.51 |
| Former or Current | 132/163 | 1.0 | 270/223 | 1.25 (0.88–1.79) | 135/128 | 1.48 (1.09–2.02) | 0.18 | |
| BMI | ||||||||
| <25 | 75/88 | 1.0 | 157/145 | 1.23 (0.82–1.86) | 63/60 | 1.16 (0.70–1.92 | 0.51 | 0.69 |
| ≥25 | 84/109 | 1.0 | 160/131 | 1.52 (1.03–2.24) | 90/89 | 1.21 (0.79–1.87) | 0.37 | |
| Family history of prostate cancer | ||||||||
| Without | 88/147 | 1.0 | 186/208 | 1.34 (0.94–1.91) | 72/123 | 0.88 (0.58–1.34) | 0.64 | 0.67 |
| With | 46/21 | 1.0 | 64/28 | 1.11 (0.53–2.30) | 38/14 | 1.14 (0.48–2.68) | 0.76 | |
a
Adjusted for age and education.