Plasma concentration of α-klotho in patients with uncomplicated pregnancy, SGA, and preeclampsia, with and without SGA. Women with PE and SGA [947.6 pg/ml IQR: (762 – 2013)] and those with SGA without PE [1000.6 pg/ml IQR: (585 – 1567)] had a lower median plasma concentration of α-klotho than uncomplicated pregnancies [1206 pg/ml IQR: (894 – 2012)]; p=0.02 and p =0.005, respectively). However, there was no a significant difference in the median concentration of α-klotho between patients with PE without an SGA neonate [1177.3 pg/ml IQR: (762.4 – 2013.4)] and women with uncomplicated pregnancies (p=0.47).