Table 1.
Univariate analysis of predictors of any intracranial hemorrhage after endovascular stroke therapy
| Variable | Any intracranial hemorrhage (n=363) (N (%)) | No hemorrhage (n=759) (N (%)) | p Value |
|---|---|---|---|
| Demographics | |||
| Age (years) (mean ±SD) | 67±15 | 66±15 | 0.49 |
| NIHSS (mean±SD) | 17±5 | 16±6 | 0.001 |
| Female | 174 (48) | 366 (48) | 0.94 |
| Diabetes mellitus | 109 (30) | 156 (20) | 0.0001 |
| Hypertension | 255 (71) | 518 (68) | 0.53 |
| Atrial fibrillation | 148 (41) | 265 (35) | 0.05 |
| Time to treatment (min) (mean±SD) | 312±157 | 296±162 | 0.15 |
| TIMI 2–3 recanalization | 247 (68) | 520 (69) | 0.89 |
| Clot location | |||
| M1 MCA | 192 (53) | 369 (49) | 0.20 |
| Carotid terminus | 72 (20) | 142 (19) | 0.69 |
| Tandem occlusion | 47 (13) | 94 (12) | 0.43 |
| M2 MCA | 43 (12) | 129 (17) | 0.03 |
| Extracranial ICA | 10 (3) | 25 (3) | 0.71 |
| Therapy | |||
| IV tPA | 137 (38) | 234 (31) | 0.025 |
| Merci embolectomy | 130 (36) | 233 (30) | 0.002 |
| Penumbra thrombectomy | 42 (11) | 88 (12) | 0.82 |
| Angioplasty | 97 (27) | 189 (25) | 0.56 |
| Stent placement | 70 (19) | 145 (19) | 0.51 |
| IA tPA | 194 (53) | 408 (54) | 0.49 |
| Pharmacologic therapy only | 73 (20) | 191 (25) | 0.07 |
| Mechanical therapy only | 91 (25) | 184 (24) | 0.41 |
| Multimodal therapy | 199 (54) | 385 (51) | 0.20 |
ICA, internal carotid artery; MCA, middle cerebral artery; NIHSS, National Institutes of Health Stroke Scale; TIMI, Thrombolysis in Myocardial Infarction; tPA, tissue plasminogen activator.