Table 1.
Fold change expression value from AHR knockdown MCF-7 compared to controls.
| GENE ID | AHR-RNA-Seq | qRT-PCR |
|---|---|---|
| AHR | 0.24585 | 0.14400 ± .040 |
| CYP1A1 | 0.04738 | 0.43253 ± .215 |
| CYP1B1 | 0.44897 | 0.36685 ± .137 |
| HMGCS2 | 0.12976 | 0.53902 ± .114 |
| OAS1 | 0.13104 | 0.62920 ± .054 |
| PLA2G2 | 0.11346 | 0.42180 ± .073 |
| ABCG2 | 0.35987 | 0.51580 ± .146 |
| NRF2 | no difference | 0.55050 ± .003 |
| ALOX5 | 0.49086 | 0.47342 ± .024 |
| ALDH3A1 | 0.05942 | 0.17310 ± .067 |
| UGT1A1 | 0.31011 | 0.50581 ± .069 |
| UGT1A3 | 0.30741 | 0.43706 ± .037 |
| UGT1A4 | 0.32062 | 0.60735 ± .066 |
| UGT1A5 | 0.32055 | 0.60620 ± .079 |
| UGT1A6 | 0.32404 | 0.61148 ± .085 |
| UGT1A7 | 0.33345 | 0.53582 ± .058 |
| UGT1A8 | 0.33597 | no difference |
| UGT1A9 | 0.33357 | no difference |
| UGT1A10 | 0.33502 | no difference |
| PKD1L1 | 0.16430 | 0.29732 ± .031 |
| PYDC1 | 2.50200 | no difference |
| PGR | 1.87529 | 1.40625 ± .103 |
| MGP | 2.39768 | 1.2750 ± .034 |
| SERPIN3A | 1.92517 | 1.52785 ± .031 |
| CREB3L | 2.67290 | 1.40500 ± .018 |
| SERPIN5A | 1.88800 | 1.7890 ± .233 |
| ADORA | 2.03342 | 1.61912 ± .209 |
Column 2 is expressed as RNA-Seq ratio of AHR knockdown/control level (FDR < 10%). Column 3 is expressed as real-time qRT-PCR ratio of AHR knockdown/control normalized to GAPDH expression (P < .05).