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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Pain. 2014 Jun 28;155(9):1878–1887. doi: 10.1016/j.pain.2014.06.019

Figure 1.

Figure 1

Behavioral sensitivity after intra-articular bupivacaine given either at injury or 4 days later. (a) Paw withdrawal threshold (PWT) decreases from baseline on all days (*p<0.027) after injury with immediate intra-articular saline (inj-VEH0h), but PWT after bupivacaine treatment at the time of injury (inj-BP0h) is not different from baseline on all days, as is observed with sham (sham-VEH0h). (b) In contrast, intra-articular bupivacaine given at 4 days after injury (inj-BPd4) has no effect on PWT, with decreased PWT compared to baseline on all days (*p<0.003), similar to the injury with a saline vehicle injection (inj-VEHd4) (^p<0.0001).