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. 2014 Feb 6;66(5):709–722. doi: 10.1007/s10616-013-9687-7

Fig. 2.

Fig. 2

cGMP production process flow for pluripotent stem cell-derived products and recombinant protein production. a Bioprocess flow for recombinant protein production, b Bioprocess flow for the production of pluripotent stem cell-derived products. For both types of products, the bioprocess consists of three stages: upstream cell culture/expansion, protein production/differentiation, and downstream purification and formulation. WCB working cell bank, hPSC human pluripotent stem cell