Table 3.
Number of nucleated cells, NK cells, monocytes and DCs infused (per kg of recipient’s body weight) according to the mobilization regimen
| G-CSF alone | G-CSF + MZ | P value | |
|---|---|---|---|
| Total NC | |||
| Median | 1.17x109/kg | 0.71x109/kg | 0.0002 |
| Range | 0.33-2.99 | 0.28-1.6 | |
| NK cells | |||
| Median | 31.3x106/kg | 16.8x106/kg | 0.0016 |
| Range | 1.8-176.8 | 2.8-55.9 | |
| NK-like T cells | |||
| Median | 3.64x106/kg | 1.56x106/kg | 0.0016 |
| Range | 0.4-34.8 | 0.2-6.64 | |
| CD16- monocytes | |||
| Median | 312.2x106/kg | 226.8x106/kg | 0.34 |
| Range | 15.9-729.8 | 28.5-667.0 | |
| CD16+ monocytes | |||
| Median | 74.9x106/kg | 63.6x106/kg | 0.46 |
| Range | 1.5-231.7 | 8.3-169.6 | |
| Slan-DCs | |||
| Median | 1.40x106/kg | 0.85x106/kg | 0.0008 |
| Range | 0.5-4.14 | 0.06-1.27 | |
| CD1c+ MDC1 | |||
| Median | 0.84x106/kg | 0.88x106/kg | 0.88 |
| Range | 0.1-13.1 | 0.04-9.66 | |
| CD303+ pDCs | |||
| Median | 4.12x106/kg | 4.73x106/kg | 0.82 |
| Range | 0.72-13.66 | 0.61-22.9 | |
| CD141+ MDC2 | |||
| Median | 3.74x106/kg | 4.15x106/kg | 0.55 |
| Range | 0.36-14.5 | 0.33-22.4 | |
| CD304+ pDCs | |||
| Median | 3.8x106/kg | 3.1x106/kg | 0.78 |
| Range | 0.2-13.0 | 0.2-14.7 |
NC = nucleated cells; MZ = plerixafor (Mozobil®); MDC1 = type 1 myeloid DCs; MDC2 = type 2 myeloid DCs. Comparisons between groups were performed with the Mann-Whitney U test for unpaired determinations.