Table 3.
SNPs with homology to genes of putative immune function mapping near to QTL regions
| QTL | Closely mapping SNPs with putative immune function | |||||||
|---|---|---|---|---|---|---|---|---|
| LG | cM | cM | SNP | GeneID | Length | Hits | E-value | Similarity |
| 2 | 0, 21.6, 24.5, 30.5, 36.6, 53.5, 61.8* and 62.5 | 47.3 | 24034_664 | proteasome (macropain) 26 s | 991 | 20 | 3.48E-45 | 62.15% |
| 61.8 | 51997_2402 | runt protein 1a | 2649 | 2 | 5.91E-53 | 84.00% | ||
| 5 | 21.2*, 21.9, 22.3, 87* and 96.5 | 21.2 | 45605_1545 | ubiquitin domain-containing protein ubfd1 | 1764 | 20 | 5.32E-81 | 66.7% |
| 6 | 17.3* 39* and 42.8 | 38.4 | 40050_2030 | 26 s proteasome subunit s9 | 2299 | 20 | 2.33E-143 | 76.50% |
| 9 | 10.4 and 59.9 | 59.7 | 42539_708 | E3 ubiquitin-protein ligase RAD18 | 1522 | 20 | 1.62E-51 | 46.90% |
| 59.9 | 37682_953 | complement component | 1318 | 20 | 1.69E-139 | 67.30% | ||
| 11 | 24.7, 38.1 and 59.4 | 20.8 | 44253_2858 | ubiquitin protein ligase | 3938 | 20 | 0 | 64.25% |
| 38.4 | 42465_201 | mitogen-activated protein kinase organiser 1 | 853 | 20 | 2.33E-57 | 58.65% | ||
| 59.4 | 23272_344 | 26 s protease regulatory subunit | 1579 | 20 | 0 | 87.45% | ||
| 15 | 27.2 and 47.8 | 27.7 | 17687_140 | proteasome subunit alpha type-7 | 965 | 20 | 4.28E-101 | 90.05% |
| 16 | 11, 23.4, 38.1 and 39.2 | 38.1 | 52008_2116 | serine threonine-protein kinase 17b | 3652 | 20 | 7.03E-39 | 83.60% |
| 17 | 8.3, 26.7, 29 and 54** | 5.6 | 50459_2444 | interleukin enhancer-binding factor 2 | 2645 | 20 | 0 | 86.70% |
| 26.7 | 45405_1355 | stress-induced-phosphoprotein 1 (Hop or HSP70-HSP90 organising protein) | 3508 | 20 | 0 | 70.90% | ||
| 29.6 | 51513_1353 | ubiquitin conjugation factor e4 | 4762 | 20 | 0 | 68.60% | ||
| 56.3 | 49912_5110 | mitogen activated protein kinase | 7539 | 20 | 7.36E-150 | 75.90% | ||
| 19 | 34.8, 44.5, 70.9 and 82.4* | 28 | 35516_4536 | hect e3 ubiquitin | 4790 | 20 | 0 | 66.25% |
| 37.8 | 47403_548 | heat shock protein isoform a | 1612 | 20 | 6.27E-25 | 64.90% | ||
| 68.5 | 52376_14757 | hect e3 ubiquitin | 16975 | 20 | 0 | 80.55% | ||
| 81.8 | 38683_977 | ubiquitin conjugating enzyme 7 interacting protein | 1048 | 20 | 8.96E-79 | 64.65% | ||
| 95.2 | 48349_91 | proteasome (macropain) 26 s non- 2 | 3200 | 20 | 0 | 74.85% | ||
| 21 | 20.1, 26, 28.5, 28.8 and 89.5 | 80.7 | 46753_1347 | e3 ubiquitin-protein ligase shprh | 1490 | 20 | 3.22E-105 | 70.25% |
| 22 | 9.1, 20.8, 27.9** | 26 | 42578_2554 | Mitogen-activated protein kinase-binding protein 1 | 2589 | 20 | 0 | 79.6% |
| 27.9 | 52279_11861 | Serine threonine-protein kinase smg1 | 14868 | 20 | 0 | 54.7% | ||
| 30.3 | 50961_705 | IGF2 mRNA binding protein | 6075 | 20 | 3.02E-138 | 68.90% | ||
| 24 | 0.4 and 50.3 | 44.9 | 51084_1046 | ubiquitin-conjugating enzyme e2 c | 3227 | 20 | 2.73E-63 | 80.10% |
| 25 | 0 | 4.7 | 51361_1388 | inhibitor of kappa light polypeptide gene enhancer in b-kinase complex-associated protein | 4354 | 20 | 1.74E-116 | 57.05% |
| 28 | 20.8 and 30.6 | 12.6 | 30698_651 | map kinase-activated protein kinase 2-like isoform 2 | 1544 | 20 | 6.12E-139 | 84.45% |
| 29 | 29.7, 44 and 53.7 | 44 | 49666_3836 | 26 s proteasome non-atpase regulatory subunit 11-like | 4562 | 20 | 3.62E-64 | 60.15% |
| 32 | 36.6 | 37.5 | 49114_4840 | ubiquitin carboxyl-terminal hydrolase 47 | 6432 | 20 | 0 | 65.70% |
| 43 | 0.4* | 2.2 | 45153_220 | aax63905c-type lectin protein | 1167 | 20 | 8.30E-15 | 43.75% |
*P <0.05; **P <0.01 after Bonferroni correction. GeneID, identity allocated by blast2go using consensus annotations for the top hits. Length, length of query contig sequence. Hits, number of sequences found to match query (maximum 20). E-value, minimum e-value (probability of alignment occurring by chance) recorded for a hit. Similarity, percent mean similarity recorded across hits.