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. 2014 Aug 30;15(1):744. doi: 10.1186/1471-2164-15-744

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© Liu et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Hierarchical clustering analysis of the 1417 DEGs between Apis mellifera and Apis cerana . For each gene, the TPM mean value of the two biological replicates at each stage was used to calculate the expression ratio between Apis mellifera and Apis cerana, i.e., TPM _{Apis mellifera} / TPM _{Apis cerana.} If the value of TPM _{Apis cerana} was 0, it was replaced by 0.01. This ratio was log2-transformed and used for the clustering analysis, which was performed using the Cluster 3.0 and Treeview programs. Red represents up-regulated expression in Apis mellifera. Green represents up-regulated expression in Apis cerana.