Table 2.
Biochemical and Hematological Parameters
LPS | LPS/FR | LPS/FR/LNNA | |
---|---|---|---|
Arterial lactate (mmol.l−1) | 7.92 ± 1.30 | 3.42 ± 0.44* | 3.56 ± 0.73* |
pH | 7.25 ± 0.04 | 7.33 ± 0.03* | 7.18 ± 0.07*§ |
Bicarbonate (mmol.l−1) | 21.50 ± 1.00 | 23.25 ± 0.95 | 22.95 ± 3.30 |
Base excess (mmol.l−1) | −4.7 ± 3.3 | −2.1 ± 0.9* | −4.4 ± 0.3§ |
Hematocrit (%) | 55.75 ± 1.70 | 50.00 ± 2.70* | 47.70 ± 1.33* |
Blood Glucose (mg.dl−1) | 32.00 ± 9.20 | 45.00 ± 11.22* | 38.20 ± 7.48 |
Leukometry (n/mm3) | 1,553 ± 493 | 3,305 ± 675* | 2,330 ± 457 |
Blood sampling for biochemical and hematological analysis was performed in all groups at the end of the study period (t = 3 h). Data are presented as means ± SD for each group. LPS, endotoxemic animals (n = 10); LPS/FR, endotoxemic and fluid resuscitated animals (n = 10); LPS/FR/LNNA, endotoxemic, fluid resuscitated, and L-NNA + L-Arginine treated animals (n = 10). *p <0.05 vs. LPS group; §p <0.05 vs. LPS/FR group.