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Specific activities (picomoles of product per picomole of IN per hour) of mutant IN proteins
| IN | Disintegration | r2 | 3′-end processing-strand transfer | r2 |
|---|---|---|---|---|
| Reference | 0.10 | 0.97 | 0.07 | 0.99 |
| C280S | 0.05 | 0.95 | 0.02 | 0.99 |
| T66I | 0.06 | 0.91 | 0.03 | 0.91 |
| S153Y | 0.04 | 0.92 | 0.02 | 0.93 |
| M154I | 0.23 | 0.98 | 0.11 | 0.97 |
| T66I-M154I | 0.06 | 0.99 | 0.03 | 0.99 |
| T66I-S153Y | NDa | ND | ND | ND |
ND, not determined.
