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. 2014 Aug 20;2014:247372. doi: 10.1155/2014/247372

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Copyright © 2014 Saren Gaowa et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Correlation between Th17/Treg ratios and related cytokines; expression of ROR γt and Foxp3 mRNA and markers of disease severity in patients with CTD-aPAH. (a) Ratios of Treg to CD4⁺ cells negatively correlate with ratios of Th17 to CD4⁺ cells. (b) Ratios of Th17/Treg positively correlate with IL-17 concentrations. (c) Ratios of Th17/Treg positively correlate with expression of ROR γt mRNA. (d) Ratios of Th17/Treg negatively correlate with TGF-β concentrations. (e) Ratios of Th17/Treg negatively correlate with expression of Foxp3 mRNA. (f) Ratios of Th17/Treg positively correlate with levels of sPAP. (g) Ratios of Th17/Treg positively correlate with NT-pro BNP concentrations.