Table 2.
Pathway mapping of TQ-phosphorylated targets by Annotation cluster3
| Database | Pathway | p-Value | Genes identified by peptide array |
|---|---|---|---|
| KEGG_PATHWAY | T cell receptor signaling pathway | 0.001971 | PDK1, AKT1, RAF1, PAK1*, MAP3K7 |
| PANTHER_PATHWAY | Angiogenesis | 0.008722 | AKT1, TCF7L2, APC, RAF1, PAK1, CTNNB1, NOS1 |
| KEGG_PATHWAY | MAPK signaling pathway | 0.041478 | MAX, AKT1, RAF1, PAK1, MAP3K7 |
| KEGG_PATHWAY | Chemokine signaling pathway | 0.042726 | AKT1, CCR2, RAF1, PAK1 |
| KEGG_PATHWAY | Renal cell carcinoma | 0.053539 | AKT1, RAF1, PAK1 |
| PANTHER_PATHWAY | Ras Pathway | 0.054889 | AKT1, RAF1, PAK1, MAP3K7 |
| BIOCARTA | Influence of Ras and Rho proteins on G1 to S Transition | 0.055681 | AKT1, RAF1, PAK1 |
| KEGG_PATHWAY | ErbB signaling pathway | 0.079412 | AKT1, RAF1, PAK1 |
| KEGG_PATHWAY | Focal adhesion | 0.091138 | AKT1, RAF1, PAK1, CTNNB1 |
| KEGG_PATHWAY | Fc gamma R-mediated phagocytosis | 0.093575 | AKT1, RAF1, PAK1 |
| BIOCARTA | MAPKinase Signaling Pathway | 0.094598 | MAX, RAF1, PAK1, MAP3K7 |
| PANTHER_PATHWAY | Inflammation mediated by chemokine and cytokine signaling pathway | 0.229979 | AKT1, CCR2, RAF1, PAK1, MAP3K7 |
| PANTHER_PATHWAY | T cell activation | 0.27141 | AKT1, RAF1, PAK1 |
*PAK1 is given in bold letters.