FIG. 2.

SQL derivatives are potent HIV-1 inhibitors that are weakly cytotoxic. HeLa P4 cells were infected with NL43 in the presence of increasing drug concentrations. First, β-Gal overproduction was quantified by CPRG assay (continuous lines); second, cell survival was measured by MTT assay (dashed lines) 72 h after infection. Triangles, FZ41; squares, L-731988. Curves are the means of at least three experiments, and results are expressed as percentages of the value for the untreated infected cells.