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Representative immunohistochemical staining for CXCL12 and CXCR4 in breast cancer. Positive CXCL12 immunostaining was seen in invasive breast cancer; the patterns of CXCL12 expression were mixed nuclear/cytoplasmic staining. Positive CXCR4 immunostaining was seen in invasive breast cancer; the patterns of CXCR4 expression were mixed membrane/cytoplasmic staining. Original magnification, all ×200
