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The presence of gene hypermethylation in the central (A) and peripheral parts (B) of the tumor, as well in the surgical margin (C)
| A | B | C | |
|---|---|---|---|
| CDH1 | 20/53 | 24/53 | 14/53 |
| (37.7 %) | (45.3 %) | (26.4 %) | |
| p16 | 14/53 | 18/53 | 10/53 |
| (26.4 %) | (33.9 %) | (18.8 %) | |
| RARbeta | 4/53 | 0 | 3/53 |
| (7.5 %) | (5.6 %) | ||
| FHIT | 1/53 | 1/53 | 1/53 |
| (1.8 %) | (1.8 %) | (1.8 %) | |
| ATM | 0 | 0 | 0 |
