TABLE 1.
Gal expression does not affect susceptibility of ST-IOWA cells to retrovirus infectiona
| Target cell line | Infectivity of retrovirus pseudotype (IU/ml)
|
|||||
|---|---|---|---|---|---|---|
| PERV-A | PERV-A 14/220 | PERV-B | PERV-C | RD114 | GALV | |
| ST-IOWA+/+ | 3 × 103 | 8 × 103 | 3 × 102 | 2 × 103 | 2 × 104 | 3 × 104 |
| ST-IOWA−/− | 3 × 103 | 6 × 103 | 4 × 102 | 3 × 103 | 2 × 104 | 4 × 104 |
a
Titers of cell-free retrovirus LacZ pseudotypes were determined on wild-type and GTTA1-null ST-IOWA cells. Quantitative analysis of susceptibility to MLV-A was not possible due to the low susceptibility of ST-IOWA cells (not shown). However, despite the low titers observed for MLV-A on porcine cells, the results suggested that Gal also had no effect on the susceptibility to this virus.