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. 2014 Aug 24;2014:104823. doi: 10.1155/2014/104823

Table 4.

The inhibition constant (pK i) of ligand binding with HDAC class II Homo sapiens.

Ligand Inhibition constant (pK i)
HDAC4 HDAC5 HDAC6 HDAC7 HDAC9 HDAC10
Nova2 (9058064-6) 18,82 21,09 21,44 22,82 18,39 17,49
Nova2 (95752-88-8) 13,30 23,07 21,03 20,50 19,48 18,92
Nova2 (88765-82-6) 17,21 21,29 20,54 18,51 17,63 16,99
Nova2 (Unique10) 17,33 21,23 20,09 19,42 17,77 15,23
Nova2 (16876-27-0) 12,36 20,20 18,86 17,71 18,07 16,64
Nova2 (513246-99-6) 16,53 20,81 19,68 19,47 18,15 15,85
Nova2 (Unique80) 16,13 18,21 19,53 17,86 17,07 15,18
Nova2 (279262-23-6) 16,13 20,01 18,97 19,73 17,67 15,07
SAHA 10,15 12,59 11,19 10,59 11,80 11,20
TSA 10,68 11,08 10,70 9,84 10,40 9,48