Table 4.
Ligand | Inhibition constant (pK i) | |||||
---|---|---|---|---|---|---|
HDAC4 | HDAC5 | HDAC6 | HDAC7 | HDAC9 | HDAC10 | |
Nova2 (9058064-6) | 18,82 | 21,09 | 21,44 | 22,82 | 18,39 | 17,49 |
Nova2 (95752-88-8) | 13,30 | 23,07 | 21,03 | 20,50 | 19,48 | 18,92 |
Nova2 (88765-82-6) | 17,21 | 21,29 | 20,54 | 18,51 | 17,63 | 16,99 |
Nova2 (Unique10) | 17,33 | 21,23 | 20,09 | 19,42 | 17,77 | 15,23 |
Nova2 (16876-27-0) | 12,36 | 20,20 | 18,86 | 17,71 | 18,07 | 16,64 |
Nova2 (513246-99-6) | 16,53 | 20,81 | 19,68 | 19,47 | 18,15 | 15,85 |
Nova2 (Unique80) | 16,13 | 18,21 | 19,53 | 17,86 | 17,07 | 15,18 |
Nova2 (279262-23-6) | 16,13 | 20,01 | 18,97 | 19,73 | 17,67 | 15,07 |
SAHA | 10,15 | 12,59 | 11,19 | 10,59 | 11,80 | 11,20 |
TSA | 10,68 | 11,08 | 10,70 | 9,84 | 10,40 | 9,48 |