Table 8.
Carcinogenicity and mutagenicity of the best ligands.
| Ligand | Potential carcinogen based QSAR | Genotoxic carcinogenicity | Nongenotoxic carcinogenicity | Potential S. typhimurium mutagenicity |
|---|---|---|---|---|
| Nova2 (9058064-6) | No | Negative | Negative | No |
| Nova2 (95752-88-8) | No | Negative | Negative | No |
| Nova2 (88765-82-6) | No | Negative | Negative | No |
| Nova2 (Unique10) | No | Negative | Negative | No |
| Nova2 (16876-27-0) | No | Negative | Negative | No |
| Nova2 (513246-99-6) | No | Negative | Negative | No |
| Nova2 (Unique80) | No | Negative | Negative | No |
| Nova2 (279262-23-6) | No | Negative | Negative | No |
| SAHA | No | Negative | Negative | No |
| TSA | No | Positive | Negative | Yes |