TABLE 4.

Intramolecular competition for initiation on linear dimeric templates

Polarity of templatea	Ratio of marked RNA to unmarked RNA after replication was initiated inb:
	δ293 cells at day:			Huh7 cells at day:
	2	4	6	2	4	6
Antigenomic	12.0	15.4	15.5	—	7.2	10.1
Genomic	5.7	7.5	4.4	—	4.6	4.2

^aThe antigenomic RNA template was a dimer with ends located at position 841 (BoxI). The 5′ monomer was unmarked and the 3′ monomer was marked, as indicated in Fig. 3. The genomic RNA template was a dimer with ends located at position 714 (NarI), with the 5′ monomer unmarked and the 3′ monomer marked.

^bDetails of the transfection and subsequent quantitation are as given in Table 3. —, not detected.