Table 4.
Effect of oxytocin augmentation on umbilical cord plasma purines and MDA
| Vaginal birth, no oxytocin | Vaginal birth with oxytocin | P-valuea | |
|---|---|---|---|
| Hypoxanthine (μM) | 14.8 ± 13.7 (n = 25) |
13.2 ± 11.7 (n = 44) |
0.736 |
| Xanthine (μM) | 5.3 ± 3.9 (n = 18) |
3.2 ± 3.5 (n = 29) |
0.023 |
| Uric acid (μM) | 277.9 ± 61.5 (n = 41) |
290.6 ± 75.3 (n = 75) |
0.566 |
| MDA (μM) | 2.4 ± 0.6 (n = 11) |
3.5 ± 1.2 (n = 21) |
0.002 |
| Clinical variables | |||
| Frequency of uterine contractions that were longer than 2 min in the last 2 h of labor | 0 (median) (n = 20) |
1 (median) (n = 44) |
0.882 |
| Frequency of uterine contractions that occurred more than five times in 10 min in the last 2 h of labor | 0 (median) (n = 20) |
0 (median) (n = 44) |
0.550 |
| Frequency of uterine contractions that occurred within 1 min of each other in the last 2 h of labor | 11 (median) (n = 25) |
18 (median) (n = 44) |
0.048 |
| Length of labor (hours) | 18.6 ± 10.6 (n = 22) |
24.1±15.5 (n = 47) |
0.088 |
Abbreviation: MDA, Malondialdehyde.
Mean ± s.d.
a
Mann – Whitney.
Bold values are statistically significant.