Table 2.
Thermodynamic parameters, binding constant (K), and number of binding sites (n) estimated for the interaction between recombinant arginine kinase of Trypanosoma brucei (rTbAK) and gallotannin.
| Inhibitors | T (K) | K (L mol−1) | n | R a | ΔH o (KJ/mol) | ΔG o (KJ/mol) | ΔS o (KJ/mol) |
|---|---|---|---|---|---|---|---|
| Gallotannin | 298 | 3.7 × 104 | 1.2176 | 0.9494 | −8.40 | 8.12 | 55.60 |
| 303 | 3.5 × 104 | 1.3381 | 0.9713 | 8.45 | 55.60 |
aThe correlation coefficient.