Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Scheme showing the potential of APE1 as an important modulator in human diseases. APE1 abnormality is known to be associated with the induction of various lethal diseases including cancer. In particular, gene-environment interaction between APE1 malfunction and several environmental factors increases the carcinogenic risk, leading to cancer development. Thus, APE1 can be suggested as one of the potential markers for risk prediction of environmental carcinogenesis.
