Table 1.
Baseline characteristics of placebo and statin patients.
| Placebo | Statin | P value | |
|---|---|---|---|
| n | 26 | 25 | |
| Age (years) | 56 ± 9 | 51 ± 12 | NS |
| Male gender (%) | 73 | 84 | NS |
| BMI (kg/m²) | 28.70 ± 3.94 | 28.28 ± 5.12 | NS |
| History | |||
| Smoking (%) | 50.0 | 60.0 | NS |
| Alcohol (%) | 38.5 | 56.0 | NS |
| Diabetes (%) | 0.0 | 4.0 | NS |
| Dyslipidemia (%) | 3.9 | 12.0 | NS |
| Respiratory characteristics | |||
| AHI (n/h) | 45.47 ± 13.10 | 43.26 ± 19.19 | NS |
| Mean SaO2 (%) | 92.57 ± 1.44 | 92.70 ± 2.40 | NS |
| SaO2 < 90% (%) | 10.33 ± 13.20 | 11.66 ± 18.11 | NS |
| Clinical BP | |||
| SBP (mmHg) | 127.67 ± 15.27 | 127.78 ± 15.07 | NS |
| DBP (mmHg) | 79.02 ± 11.61 | 79.16 ± 11.60 | NS |
| MAP (mmHg) | 95.22 ± 11.93 | 95.37 ± 12.21 | NS |
| HR (bpm) | 63 ± 8 | 64 ± 10 | NS |
| Biological parameters | |||
| Total cholesterol (g/L) | 2.25 ± 0.64 | 2.46 ± 0.94 | NS |
| LDL cholesterol (g/L) | 1.41 ± 0.45 | 1.60 ± 0.67 | NS |
| HDL cholesterol (g/L) | 0.54 ± 0.23 | 0.74 ± 0.52∗ | 0.011 |
| Triglycerides (g/L) | 1.55 ± 1.10 | 1.16 ± 0.59 | NS |
Data are mean ± SD or percentage. BMI, body mass index; SaO2, oxygen saturation; SaO2 < 90%, percentage of recording time spent at a SaO2 < 90%; BP, blood pressure; SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL, low-density lipoprotein; HDL, high-density lipoprotein; HR, heart rate. *P < 0.05 by Student or Mann-Whitney test. For qualitative data, a Chi-2 test or a Fisher test was performed. NS, not significant.