Table 2.
Variable | WBTH (n = 36) |
Non-WBTH (n = 32) |
P value |
---|---|---|---|
Primary outcomes (mean ± SD) | |||
DOL enteral feeds started | 5.6 ± 2 | 6 ± 3 | 0.12 |
DOL full enteral feeds reached | 10.1 ± 3.7 | 11.3 ± 5.6 | 0.02∗ |
DOL full oral feeds reached | 11.5 ± 5.6 | 12.7 ± 6.7 | 0.01∗ |
| |||
Secondary outcomes (%) | |||
Never started enteral feeds | 5.6 | 28.1 | 0.02∗ |
Never reached full enteral feeds | 5.6 | 37.5 | 0.002∗ |
Never reached full oral feeds | 19.4 | 56.3 | 0.002∗ |
Death | 5.7 | 32.3 | 0.009∗ |
GT | 5.6 | 15.6 | 0.24 |
Combined death and GT | 11.1 | 46.9 | 0.001∗ |
Discharged with gavage feeds | 5.6 | 9.4 | 0.66 |
Combined death and discharged with gavage feeds | 11.1 | 43.8 | 0.005∗ |
NEC+ | 0 | 9.4 | 0.1 |
ECMO | 8.3 | 0 | 0.24 |
Elevated liver enzymes† | 63.9 | 63 | 0.94 |
Elevated coagulation parameters∞ | 100 | 91.3 | 0.15 |
Days to hospital discharge or death | 16.9 ± 11.1 | 16.9 ± 12 | 1 |
∗Significance defined by P < 0.05.
+Grossly bloody stool (Bell's stage IIA or greater).
†Aspartate aminotransferase level >200 IU and alanine aminotransferase level >100 IU.
∞Prothrombin time >15.6 seconds and partial thromboplastin time >41.5 seconds.