Table 3.
Variable | WBTH (n = 70) |
Non-WBTH (n = 78) |
P value |
---|---|---|---|
Primary outcomes (mean ± SD) | |||
DOL enteral feeds started | 5.4 ± 2.2 | 5.8 ± 2.6 | 0.39 |
DOL full enteral feeds reached | 9.9 ± 4.3 | 10.4 ± 6.1 | 0.12 |
DOL full oral feeds reached | 11.4 ± 6.2 | 11.4 ± 6.9 | 0.13 |
| |||
Secondary outcomes (%) | |||
Never started enteral feeds | 12.9 | 21.8 | 0.15 |
Never reached full enteral feeds | 12.9 | 25.6 | 0.05 |
Never reached full oral feeds | 25.7 | 42.3 | 0.03∗ |
Death | 15.9 | 23.4 | 0.26 |
GT | 10 | 12.8 | 0.29 |
Combined death and GT | 26 | 36.4 | 0.21 |
Discharged with gavage feeds | 2.9 | 7.7 | 0.28 |
Combined death and discharged with gavage feeds | 17.4 | 31.2 | 0.06 |
NEC+ | 2.9 | 5.1 | 0.68 |
ECMO | 5.7 | 1.3 | 0.19 |
Elevated liver enzymes† | 62.9 | 54.6 | 0.33 |
Elevated coagulation parameters∞ | 100 | 80.4 | 0.0001∗ |
Days to hospital discharge or death | 15.8 ± 10.2 | 16.2 ± 10.9 | 0.83 |
∗Significance defined by P < 0.05.
+Grossly bloody stool (Bell's stage IIA or greater).
†Aspartate aminotransferase level >200 IU and alanine aminotransferase level >100 IU.
∞Prothrombin time >15.6 seconds and partial thromboplastin time >41.5 seconds.