Table 1. Glucose uptake in 15-month-old BACHD and WT mice.
| Region (cluster number) | WT | BACHD | % Change | Statistics (P-value) |
|---|---|---|---|---|
| Caudate putamen (right-1) | 241.0±3.0 | 223.9±2.2 | −7.1 | 0.00094 |
| Caudate putamen (left-2) | 234.8±2.7 | 213.7±3.5 | −9.0 | 0.00074 |
| Dentate gyrus (right-3) | 197.2±1.5 | 182.7±2.1 | −7.4 | 0.00021 |
| Dentate gyrus (left-4) | 196.9±2.0 | 181.3±2.5 | −8.0 | 0.00062 |
| Cerebellum (5) | 179.5±2.7 | 158.6±3.1 | −11.6 | 0.00046 |
| Hypothalamus+zona incerta (6) | 212.1±5.0 | 232.4±1.3 | +9.6 | 7.8 × 10−6 |
| Activated barrel cortex | 231.8±4.5 | 252.6±3.0 | +9.0 | 0.003 |
Regional 2-DG ([14C]-2-Deoxyglucose) uptake values, mean±s.e.m. (nCi/g), percentage difference, and associated P-values measured between 15-month-old BACHD and WT (wild-type) mice, using autoradiography three-dimensional reconstruction and voxel-wise statistical analysis (see Materials and Methods).