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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Neuropharmacology. 2014 Jun 9;85:357–366. doi: 10.1016/j.neuropharm.2014.05.041

Figure 3. Daily neonatal MTII reduced male juvenile play bouts.

Figure 3

Between PND24-29, juvenile prairie voles injected with MTII or saline from PND1-7 were singly housed and tested for play behaviors for 10min with a novel untreated stimulus animal over a 3d period. Bouts of initiated play increased over time in saline males, but remained stable in MTII males (A). On the third testing day, MTII male play was significantly lower than saline male play (B), which was driven by a decrease in boxing and wrestling/tackling (C). MTII treated females displayed greater levels of sniffing than saline females on the third day of testing (D). Asterisks in A-B indicate post-hoc Student’s t-tests with p<0.05 and in C-D indicate Mann-Whitney U tests with p<0.05. AG, aggressive grooming; B, boxing; C, chasing; Pi, Pinning; Po, pouncing; PB, pulling/biting; Su, supine; WT, wrestling/tackling; Allo, allogrooming; GI, genital investigation; H, huddling; Sn, sniffing; SC, social contact.