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3C assay demonstrates looping between ASC192 and POU2F1. (A) Black ticks indicate locations of primers designed to capture long-range DNA interactions with ASC192. Locus-wide relative interaction frequencies reveal that ASC192 interacts most strongly with the two promoters of POU2F1. Error bars represent one standard deviation. (B) DNase-seq signal at ASC192 and the POU2F1promoter regions indicate an open chromatin conformation in human fetal brain.
