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Histologic and immunohistochemical characterization of skull base chordomas. H&E stains showed both conventional (A, B) and chondroid (C) histologic subtypes of chordomas in the cohort. 32% had a prominent solid component (B), 32% showed elevated Ki67 PI (D), and 44% showed increased p53 accumulation (E). EGFR expression, in contrast, was seen in only 8% of cases (F).
