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. Author manuscript; available in PMC: 2014 Sep 9.
Published in final edited form as: Arch Pathol Lab Med. 2010 Aug;134(8):1170–1176. doi: 10.1043/2009-0380-OA.1

Figure 3.

Figure 3

Overall survival of skull base chordomas with proliferative and molecular alterations. Chordomas with elevated Ki67 PI showed a significant reduction in overall survival (A, *P = 0.005), as did cases with large LOH on 9p (B, *P = 0.03). Homozygous deletion of 9p21 trended toward correlation with shorter overall survival (C). LOH on 1p (D), 10q23 (E), or 17p13 (F), on the other hand, showed no differences in survival; neither did 1p36 hemizygous deletion via FISH, chromosome 9 monosomy, p53 protein accumulation, EGFR expression, presence of a solid tumor component, or histologic subtype (not shown).