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. 2014 Sep 9;8:96. doi: 10.3389/fnana.2014.00096

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Copyright © 2014 Benitez, Barbizan, Spejo, Ferreira, Barraviera, Góes and de Oliveira.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A–D) Immunohistochemistry for VGLUT1. (A) Contralateral side. (B) IL side of RZ alone group. (C) IL side of RZ+FS group. (D) IL side of RZ+FS+MC group. White dotted ellipse represents the injury/reimplantation site. Orange dotted circle represents lamina IX. (E–G) Schematic representation of the proposed regeneration process following dorsal root reimplantation with fibrin sealant associated with mononuclear MC therapy. (E) RZ group. (F) RZ+FS group. (G) RZ+FS+SC group. FS, fibrin sealant; IL, ispsilateral; MC, mononuclear cells; RZ, rhizotomy. Scale bar = 500 μm.