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Human pancreatic cancer cell lines used in this study
| Cell lines | KRAS | TP53 | CDKN2A/p16 | SMAD4/DPC4 |
|---|---|---|---|---|
| MIA PaCa-2 | 12 Cys | 248 Trp | HD | WT |
| CFPAC1 | 12 Val | 242 Arg | WT | HD |
| Panc-1 | 12 Asp | 273 His | HD | WT |
| BxPC-3 | WT | 220 Cys | WT | HD |
KRAS (v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog); TP53 (encoding the p53 protein); CDKN2A/p16 (p16 or p16INK4a); SMAD4/DPC4 (SMAD family member 4/deleted in pancreatic carcinoma locus 4).
WT, wild-type; HD, homozygous deletion.
