Figure 2.

Comparison of RNAi screens for modifiers of protein misfolding diseases. A Venn diagram highlighting overlapping hits from other RNAi screens using models for diseases caused by protein aggregation or misfolding. Wang et al. (26) study (A), current study (B), Nollen et al. (22) study (C) and Lejune et al. (29) study (D). The details of each screen are summarized in Supplementary Material, Table S2. Numbers within parenthesis represent the total number of hits reported. Numbers not in parentheses represent number of overlapping hits with other screens. *F48F7.1 (alg-1); ^†C14B9.7 (rpl-21), F42C5.1 (rpl-8), Y46G5.4 (phi-10); ^‡C07B5.5 (nuc-1), Y47D3B.2 (hum-5), ZC395.10.