Table 4. Multivariate logistic regression analysis (odds ratios reported).
Logistic analyses at 36 months & 84 months follow-up | |||
Dependant: Deceased at date of censoring = 1 and 0 otherwise | Overall | 36+ months | 84+ months |
Health provider: Public | 1 | 1 | 1 |
Private/Mixed | 0.94 (CI:0.64, 1.36) | 0.93 (CI:0.64, 1.36) | 1.04 (CI: 0.57, 1.90) |
Age: 35–54 years | 1 | 1 | 1 |
55–69 years | 2.06*** (CI:1.62, 2.62) | 2.01*** (CI: 1.53, 2.64) | 2.08*** (CI:1.34, 3.25) |
70 and over years | 9.08*** (CI:7.01, 11.74) | 9.23*** (CI: 6.86, 12.42) | 11.26*** (CI:7.05, 17.96) |
Interactions: 55–69 years/Private | 0.77 (CI: 0.55, 1.10) | 0.73* (CI:0.51, 1.05) | 0.66 (CI:0.37, 1.17) |
70 years and over/Private | 0.54*** (CI:0.39, 0.76) | 0.51*** (CI:0.37, 0.72) | 0.48*** (CI:0.28, 0.82) |
Socio-economic status: SES1 | 1 | 1 | 1 |
SES2 | 1.17*** (CI:1.05, 1.30) | 1.22*** (CI:1.08, 1.37) | 1.33*** (CI:1.15, 1.53) |
SES3 | 1.12*** (CI:1.02, 1.24) | 1.14** (CI:1.02, 1.27) | 1.22*** (CI:1.08, 1.37) |
SES4 | 1.08 (CI:0.97, 1.19) | 1.10 (CI:0.97, 1.24) | 1.19** (1.02, 1.39) |
SES5 | 1.20*** (CI:1.09, 1.33) | 1.26*** (CI:1.14, 1.39) | 1.34*** (CI:1.18, 1.52) |
SES Unknown | 0.89 (CI:0.76, 1.05) | 1.02 (CI:0.87, 1.19) | 1.24** (CI:1.01, 1.53) |
Stage: Stage I | 1 | 1 | 1 |
Stage II | 1.21 (CI:0.94, 1.55) | 1.23 (CI:0.95, 1.59) | 1.13 (CI:0.81, 1.58) |
Stage III | 1.28 (CI:0.93, 1.78) | 1.35* (CI:0.98, 1.85) | 1.30 (CI:0.93, 1.82) |
Stage IV | 9.37*** (CI:7.16, 12.26) | 9.83*** (CI:7.61, 12.70) | 7.94*** (CI:6.30, 10.02) |
Stage Unknown | 3.21*** (CI:2.42, 4.27) | 2.88*** (CI:2.13, 3.88) | 1.95*** (CI:1.56, 2.43) |
Grade: Gleason <5 | 1 | 1 | 1 |
Gleason 5–7 | 0.70*** (0.60, 0.83) | 0.73*** (CI:0.62, 0.86) | 0.87* (CI:0.76, 1.01) |
Gleason >7 | 1.48** (CI:1.08, 2.04) | 1.85*** (CI:1.50, 2.29) | 2.47*** (CI:2.06, 2.94) |
Grade Undifferentiated | 2.13*** (CI:1.20, 3.76) | 2.87*** (CI:1.46, 5.65) | 3.50** (CI:1.03, 11.90) |
Gleason grade Unknown | 1.96*** (CI:1.53, 2.50) | 2.10*** (1.70, 2.60) | 2.21*** (CI:2.00, 2.44) |
Marital Status: Single/Divorced/Widowed | 1 | 1 | 1 |
Married | 0.80*** (CI:0.71, 0.91) | 0.75*** (CI:0.68, 0.82) | 0.71*** (CI:0.64, 0.79) |
Region: Leinster | 1 | 1 | 1 |
Ulster | 0.55*** (CI:0.45, 0.66) | 0.54*** (0.43, 0.69) | 0.56*** (0.43, 0.73) |
Connacht | 0.83*** (CI:0.72, 0.96) | 0.87** (0.76, 0.99) | 0.87 (0.68, 1.13) |
Munster | 1.31*** (CI:1.20, 1.42) | 1.30*** (1.18, 1.43) | 1.16*** (1.08, 1.24) |
MOP: Other | 1 | 1 | 1 |
Screen- opportunistic | 0.39*** (0.26, 0.58) | 0.37*** (CI:0.25, 0.57) | 0.47*** (CI:0.29, 0.77) |
Incidental | 1.08 (CI:0.85, 1.38) | 0.95 (CI:0.76, 1.18) | 0.83*** (CI:0.74, 0.93) |
Symptomatic | 1.59*** (CI:1.17, 2.17) | 1.37*** (CI:1.13, 1.67) | 1.28*** (CI:1.18, 1.40) |
Smoker at diagnosis: No | 1 | 1 | 1 |
Yes | 1.73*** (CI:1.59, 1.89) | 1.64*** (CI:1.52, 1.77) | 1.63*** (CI:1.43, 1.86) |
Number of Obs | 26816 | 21054 | 10697 |
Wald test for Stage and Gleason Grade | Chi2 (8) = 1640 (P = 0.00) | Chi2 (8) = 41488 (P = 0.00) | Chi2 (5) = 1427 (P = 0.00) |
Wald test for SES & Region | Chi2 (8) = 850 (P = 0.00) | Chi2 (8) = 3162 (P = 0.00) | Chi2 (5) = 93.91 (P = 0.00) |
% Correctly Classified | 79.80% | 78.22% | 76.37% |
Notes: 1.) Odds Ratios with clustered standard errors (Confidence Intervals in brackets).
2.) Significance: * (P<0.10), ** (P<0.05), *** (P<0.01).
3.) “SES”- Socio-economic status.
4.) Interactions between socio-economic status and healthcare provider were also included in the logistic analyses but not reported above due to lack of statistical significance across all models.