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. 2014 Sep 9;9(9):e107047. doi: 10.1371/journal.pone.0107047

Table 3. Association between TP53 rs1042522 Arg72Pro variant and NHL risk stratified by selected variables.

Variable TP53 Arg72Pro P interaction c
Arg/Arga Arg/Pro+ Pro/Proa ORb (95% CI) P
Age (year) 0.122
≤50 26/89 77/107 2.46(1.45–4.16) 0.001
>50 26/68 71/136 1.36(0.80–2.32) 0.263
Sex 0.530
Male 35/101 93/159 1.72(1.08–2.73) 0.023
Female 17/56 55/84 2.16(1.13–4.10) 0.019
Pathology NC
T-cell 16/157 34/243 2.50(0.78–2.90) 0.226
B-cell 36/157 114/243 2.02(1.31–3.10) 0.001

Note: NHL: Non-Hodgkin Lymphoma, OR: odds ratio, 95%CI: 95% confidence interval, NC: not calculated.

a

Number of case patients with genotype/number of control subjects with genotype.

b

Data were calculated by logistic regression, adjusted for sex and age, where it was appropriate.

c

P values for gene-environment interaction were calculated using the multiplicative interaction term in SPSS software.