Table 1. Comparison of the clinical features of male patients with deletion in 2p14-p16.1 that encompasses OTX1.

Subjects	1	2	3	4	5	6	7	Rajcan et al.	Hancarova et al.
Size of Deletion (Mb)	0.07	5.05	2.39	6.31	4.59	2.75	3.02	7.89	3.72
Chromosome Localization	2p15	2p15p14	2p16.1p15	2p16.1p14	2p16.1p14	2p15p14	2p15p14	2p16.1p15	2p15p14
Genomic Region (Mb, hg18)	63.13–63.20	62.82–67.87	60.98–63.37	59.92–66.23	60.91–65.51	61.42–64.17	62.74–65.76	55.33–63.23	62.01–65.73
General
Age at Evaluation (years)	10	4	9	1.75	16	14	4	7	4
Sex	Male	Male	Male	Male	Male	Male	Male	Male	Male
Developmental Delay	-	+	+	+	+	+	+	+	+
Seizures	-	-	+	-	+	-	-	-	-
Feeding Problems	-	-	+	+	+	-	-	+	+
Vision Problems	-	+	+	-	-	-	+	+	+
Recurrent Ear Infections	-	+	+	-	-	+	-	-	-
Short Stature	-	-	+	-	-	+	-	+	-
Microcephaly	-	-	-	+	+	-	-	+	+
Hypotonia	-	+	+	+	-	+	-	-	+
Urological Features
Bladder Exstrophy	+	-	-	-	-	-	-	-	-
Epispadias	+	-	-	-	-	-	-	-	-
VUR	+	-	-	-	-	-	-	+	-
Cryptorchidism	-	+	+	-	-	-	+	-	+
Small Testes	-	-	+	-	-	+	+	+	-
Absent Foreskin	-	+	-	-	-	-	-	-	-
Scrotal anomalies	-	-	+	+	-	-	-	-	-
Micropenis	-	-	+	+	-	-	-	+	-
Kidney Abnormalities	-	-	+	-	-	-	-	+	-
Facial Features
Flattened Occiput	NM	-	+	-	+	-	NM	+	+
Metopic Ridging	NM	+	+	NM	NM	-	NM	+	-
Ptosis	NM	-	+	-	+	-	+	+	-
Slanted Palpebral Fissures	NM	-	+	+	NM	-	+	+	-
Epicanthal Folds	NM	+	+	+	NM	+	NM	+	-
Prominent Nose	NM	+	+	+	+	-	+	+	+
Long, Straight Eyelashes	NM	-	+	NM	NM	+	NM	+	-
Large Ears	NM	+	+	NM	-	-	+	+	+
Thin Upper Lip	NM	+	-	-	-	-	+	-	+
Other
Nipple Abnormalities	NM	-	-	NM	+	-	-	+	-
Pes Planus	NM	-	+	-	+	-	+	-	-
Attention Deficit Behavior	NM	-	-	NM	+	+	NM	+	+

VUR  =  vesicoureteral reflux; NM  =  not mentioned.