Table 1. Genes differentially expressed by co-culture of U87 and HBMECs.
Symbol | Corrected p-value | Fold Change | Symbol | Corrected p-value | Fold Change |
PRRX2 | 3.25E-04 | 4.43* | CD36 | 3.25E-04 | −2.37 |
CTHRC1 | 0.013 | 2.06 | MBP | 7.72E-03 | −2.95 |
FILIP1L | 0.015 | 2.86 | LOC100131643 | 8.21E-03 | −2.85 |
C8orf4 | 0.015 | 2.04 | KIAA1199 | 0.0082 | −2.64 |
PDE7B | 0.020 | 2.20 | DLX5 | 0.0082 | −2.42 |
SOBP | 0.020 | 2.19 | MBTD1 | 0.0084 | −2.15 |
MTRR | 0.022 | 8.83 | KIAA0692 | 0.015 | −9.23 |
ICAM1 | 0.022 | 4.56 | GREM1 | 0.020 | −2.00 |
CXCL1 | 0.022 | 4.51 | MIR204 | 0.024 | −18.27 |
A4GALT | 0.022 | 3.84 | ZFAT | 0.024 | −2.52 |
MSI2 | 0.022 | 2.49 | ZXDA | 0.024 | −2.23 |
MXRA5 | 0.022 | 2.33 | MIR2117 | 0.026 | −3.34 |
FAM179A | 0.022 | 2.24 | ZMYM3 | 0.028 | −20.38 |
FZD9 | 0.026 | 12.33 | KLK11 | 0.029 | −3.40 |
MED15 | 0.026 | 2.24 | DIRC1 | 0.032 | −2.10 |
LOC650566 | 0.028 | 2.73 | HS3ST2 | 0.032 | −2.27 |
FNDC5 | 0.029 | 27.45 | THBS1 | 0.033 | −2.58 |
CDKN2C | 0.032 | 22.06 | C9orf96 | 0.033 | −2.29 |
CCL20 | 0.034 | 2.68 | EGR3 | 0.034 | −3.00 |
PNLIPRP3 | 0.044 | 2.25 | LOC285501 | 0.034 | −2.47 |
SLCO2A1 | 0.046 | 10.51 | RCAN2 | 0.040 | −3.04 |
LOC729666 | 0.047 | 3.22 | CD80 | 0.048 | −2.30 |
C9orf150 | 0.048 | 2.20 |
*All genes with a Benjamini-Hochberg corrected p-value<0.05 and greater than a two-fold change are shown. Fold change was calculated as: (Co-culture dataset/Computational dataset) for genes with increased expression upon co-culture, or as: −(1/(Co-culture dataset/Computational dataset)) for genes downregulated.