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. 2014 Sep 9;9(9):e107289. doi: 10.1371/journal.pone.0107289

Figure 2. Conformational states of GyrB43 along the ATP hydrolysis reaction path.

Figure 2

The various states have been trapped by co-crystallization with the appropriate nucleotides. The dimeric structures are shown in cartoon representation with semi-transparent molecular surface overlaid. Subunits are distinguished by a slight variation in colour hue. View perpendicular to the molecular dyad. (a) AMPPNP complex (PDB entry 1EI1 [13]), (b) ADP⋅Pi complex, (c) ADP⋅BeF3 complex and (d) ADP complex. Note the distinct opening angles defined by the two transducer domains with the AMPPNP and ADP complexes in a "closed" conformation, the ADP⋅BeF3 complex in a "semi-open" and the ADP⋅Pi complex in "open" conformation.