Table 1.
Patient characteristics.
| ≥VGPR/SINGLE ASCT | ≤PR/TANDEM ASCT | P-VALUE | |
|---|---|---|---|
| Number of patients | 44 | 31 | |
|
| |||
| Age at diagnosis | 0.96 | ||
| Median (range) | 56 (27–70) | 56 (36–71) | |
|
| |||
| Race | 0.76 | ||
| White | 34 | 23 | |
| Other | 10 | 8 | |
|
| |||
| Sex | 0.29 | ||
| Male | 23 | 20 | |
| Female | 21 | 11 | |
|
| |||
| Time from diagnosis to transplant, months median (range) | 7.0 (5–104) | 9.0 (5–149) | 0.053 |
|
| |||
| Prior Radiotherapy | 0.80 | ||
| Yes | 13 | 10 | |
| No | 31 | 21 | |
|
| |||
| Durie-salmon stage | 0.29 | ||
| 1A | 2 | 1 | |
| 2A | 14 | 8 | |
| 2B | 2 | 0 | |
| 3A | 16 | 17 | |
| 3B | 10 | 5 | |
|
| |||
| Response status at ASCT1 | 0.0432 | ||
| PR | 30 | 28 | |
| VGPR/CR | 9/4 | 2/1 | |
| SD | 1 | 0 | |
|
| |||
| Number of induction regimens prior to ASCT1, (%) | 0.37 | ||
| 1 | 30 (68.2) | 18 (58.1) | |
| 2 | 10 (22.7) | 12 (38.7) | |
| 3 | 4 (9.1) | 1 (3.2) | |
|
| |||
| LDH at ASCT1*, median (range) | |||
| 187 (115–693) | 334 (119–739) | 0.0141 | |
|
| |||
| B-2 microglobulin at diagnosis, Median (range) | 3.37 (1.4–26.3) | 3.77 (1.1–24.8) | 0.43 |
Note:
*
LDH at diagnosis was not available for majority of patients.
Abbreviations: VGPR, very good partial response; PR, partial response; MR, minimal response; ASCT, autologous stem cell transplant.