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Cytotoxicity EC50 values for free and encapsulated drugs in polymer nanoparticles.
| TMZ |
DOX |
|||
|---|---|---|---|---|
| U87-MG [µM] |
MDA MB468 [µM] |
U87-MG [µM] |
MDA MB468 [µM] |
|
| Free drug | 37 | >400 | 1 | 0.08 |
| PMLA-Et100/drug | 133 | 130 | 30 | 0.8 |
| PMLA-Et50H50/drug | 50 | 105 | 1 | 0.2 |
| PMLA-Bu50H50/drug | 260 | 200 | 10 | 10 |
