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. 2014 Aug 22;18(4):484. doi: 10.1186/s13054-014-0484-2

Table 1.

Laboratory characteristics of control animals and animals with peritonitis (values are given as mean ± SD)

Controls (n = 10) Wilcoxon Peritonitis (n = 10) Wilcoxon Welch rank
Baseline 27 hours ( P value) Baseline 27 hours ( P value) ( P value)
Weight (kg) 39.1 ± 3.7 40.2 ± 2.3
Core temperature (°C) 38.50 ± 0.65 40.59 ± 0.34 0.0039** 38.16 ± 0.76 40.77 ± 0.37 0.002** 0.39
Mean arterial pressure (mmHg) 76.0 ± 14.3 88.6 ± 12.7 0.002** 78.6 ± 12.5 66.5 ± 19.9 0.16 0.009**
Heart rate (bpm) 80.1 ± 16.6 82.9 ± 20.7 0.82 68.5 ± 12.2 143.9 ± 25.4 0.002** 0.00009****
Cardiac output (l/min) 5.0 ± 1.3 4.6 ± 0.6 0.50 4.5 ± 0.9 4.8 ± 1.2 0.84 0.92
Stroke volume 63.2 ± 9.3 57.7 ± 10.1 0.65 65.9 ± 7.1 39.1 ± 13.7 0.004** 0.0011**
Sodium (mmol/l) 135.5 ± 1.9 141.5 ± 2.4 0.004** 134.3 ± 2.5 131.4 ± 2.6 0.19 0.00008****
Potassium (mmol/l) 4.0 ± 0.4 4.1 ± 0.2 0.61 4.0 ± 0.2 4.1 ± 0.4 0.76 0.76
Glucose (mmol/l) 8.4 ± 1.3 5.4 ± 0.4 0.002** 9.4 ± 1.3 5.0 ± 1.0 0.002** 0.21
Lactate (mmol/l) 1.2 ± 1.1 1.1 ± 0.4 0.77 1.0 ± 0.6 1.8 ± 0.7 0.05* 0.016*
pH 7.52 ± 0.04 7.47 ± 0.02 0.002** 7.51 ± 0.04 7.41 ± 0.06 0.004** 0.010*
Bicarbonate (mmol/l) 32.6 ± 1.8 31.4 ± 3.0 0.27 32.2 ± 1.5 26.9 ± 2.8 0.004** 0.004**
Base excess (mmol/l) 9.1 ± 2.7 7.9 ± 2.8 0.39 9.3 ± 1.9 2.5 ± 3.6 0.006** 0.006**
TNFα (pg/ml) 86.6 ± 76.2 60.9 ± 22.7 0.30 69.6 ± 46.9 317.6 ± 187.8 0.006** 0.002**

Wilcoxon test was used for comparison of baseline and 27-hour measurements within each group. Welch test of ranked data was used to compare 27-hour measurements between controls and animals with peritonitis. (* = P <0.05, ** = P <0.01, **** = P <0.0001). TNFα, tumour necrosis factor alpha.