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. 2014 Aug 31;14:642. doi: 10.1186/1471-2407-14-642

Table 2.

The association of selected risk factors with time between diagnosis and major resection, early stage colorectal cancer, 1996-2009

Variable Time between diagnosis and resection (days) Univariable analysis Multivariable analysis 1
Median IQR Coef 2 95% Confidence interval Coef 2 95% Confidence interval
Age group
  15 – 44 26 (15–37) 0.00 0.00
  45 – 54 29 (17–41) 2.07 0.97 to 3.17 1.72 0.60 to 2.85
  55 – 64 30 (19–42) 3.59 2.46 to 4.72 2.92 1.76 to 4.08
  65 – 74 31 (19–43) 3.91 2.80 to 5.02 3.76 2.58 to 4.93
  75 and older 30 (16–43) 2.91 1.57 to 4.26 3.48 2.32 to 4.63
Gender
  Male 31 (19–43) 0.00
  Female 29 (16–41) -1.87 -2.30 to -1.44 -1.24 -1.54 to -0.94
Region of residence
  London 28 (17–40) 0.00
  North East 30 (19–41) 1.55 -1.67 to 4.76 1.83 0.93 to 2.73
  North West 27 (13–41) -1.07 -3.19 to 1.06 -2.21 -3.00 to -1.43
  Yorkshire and the Humber 29 (18–42) 1.39 -0.73 to 3.52 1.50 0.65 to 2.36
  East Midlands 34 (21–46) 4.12 1.98 to 6.25 2.86 2.05 to 3.68
  West Midlands 32 (20–43) 3.04 0.91 to 5.16 2.16 1.37 to 2.95
  East of England 34 (23–45) 5.10 2.19 to 8.01 3.34 2.41 to 4.27
  South East 32 (19–43) 2.26 -0.76 to 5.28 1.87 -0.38 to 4.12
  South West 27 (11–40) -2.21 -4.34 to -0.08 -2.39 -3.19 to -1.59
Ethnicity, major groups 3
  White 33 (21–43) 0.00
  Black 30 (21–42) -0.60 -4.95 to 3.75 0.57 -2.97 to 4.11
  Asian 32 (20–41) -0.92 -2.94 to 1.10 -0.66 -2.52 to 1.19
  Mixed 26 (17–35) -6.26 -10.43 to -2.09 -4.30 -8.40 to -0.20
  Other Ethnic Group 30 (18–40) -2.94 -6.44 to 0.55 -2.15 -4.99 to 0.68
  Unknown 34 (22–44) 0.47 -0.39 to 1.33 0.27 -0.80 to 1.34
Site
  Colon 28 (15–40) 0.00
  Rectosigmoid 32 (21–43) 4.48 3.61 to 5.35 4.42 3.81 to 5.03
  Rectum 36 (23–48) 7.68 5.85 to 9.52 7.57 6.10 to 9.04
Stage
  A 35 (23–46) 0.00
  B 28 (15–41) -5.83 -6.25 to -5.41 -4.12 -4.46 to -3.77
Morphology
  Adenocarcinoma 30 (18–42) 0.00
  Mucinous adenocarcinoma 28 (14–40) -2.45 -3.26 to -1.64 -0.84 -1.44 to -0.25
  Other 32 (18–43) 1.00 -0.16 to 2.16 1.18 0.23 to 2.12
  Not otherwise specified 28.5 (8–39)
Grade
  G1 28 (15–41) 0.00
  G2 30 (18–42) 1.81 0.67 to 2.94 1.16 0.27 to 2.06
  G3 28 (15–41) 0.15 -1.11 to 1.40 0.66 -0.29 to 1.62
  G4 20.5 (6–33) -7.82 -12.76 to -2.88 -6.45 -11.02 to -1.88
  Unknown 29 (13–43)
Deprivation quintile 4
  1 - least deprived 31 (19–43) 0.00
  2 31 (19–43) -0.11 -0.62 to 0.41 0.28 -0.55 to 1.11
  3 31 (19–43) -0.07 -0.67 to 0.52 0.40 -0.29 to 1.09
  4 31 (18–43) -0.33 -1.04 to 0.38 0.19 -0.55 to 0.93
  5 - most deprived 30 (17–42) -0.52 -1.84 to 0.80 0.21 -0.55 to 0.98
  Unknown 21 (9–35)
Cancer plan implementation period
  Prior to implementation 24 (12–37) 0.00
  Initialization 29 (16–42) 4.23 3.09 to 5.37 4.83 3.56 to 6.10
  Implementation 33 (22–44) 7.06 4.10 to 10.01 8.02 5.53 to 10.51

1adjusted for all the other variables in the table except ethnicity.

2coefficient - represents the additional days between diagnosis and first resection for each category compared to the reference category.

3represents only data from 2005–2009.

4based on the income component of the 2007 Index of Multiple Deprivation.