Table 2.
Variable | Time between diagnosis and resection (days) | Univariable analysis | Multivariable analysis 1 | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Median | IQR | Coef 2 | 95% Confidence interval | Coef 2 | 95% Confidence interval | |||||
Age group | ||||||||||
15 – 44 | 26 | (15–37) | 0.00 | 0.00 | ||||||
45 – 54 | 29 | (17–41) | 2.07 | 0.97 | to | 3.17 | 1.72 | 0.60 | to | 2.85 |
55 – 64 | 30 | (19–42) | 3.59 | 2.46 | to | 4.72 | 2.92 | 1.76 | to | 4.08 |
65 – 74 | 31 | (19–43) | 3.91 | 2.80 | to | 5.02 | 3.76 | 2.58 | to | 4.93 |
75 and older | 30 | (16–43) | 2.91 | 1.57 | to | 4.26 | 3.48 | 2.32 | to | 4.63 |
Gender | ||||||||||
Male | 31 | (19–43) | 0.00 | |||||||
Female | 29 | (16–41) | -1.87 | -2.30 | to | -1.44 | -1.24 | -1.54 | to | -0.94 |
Region of residence | ||||||||||
London | 28 | (17–40) | 0.00 | |||||||
North East | 30 | (19–41) | 1.55 | -1.67 | to | 4.76 | 1.83 | 0.93 | to | 2.73 |
North West | 27 | (13–41) | -1.07 | -3.19 | to | 1.06 | -2.21 | -3.00 | to | -1.43 |
Yorkshire and the Humber | 29 | (18–42) | 1.39 | -0.73 | to | 3.52 | 1.50 | 0.65 | to | 2.36 |
East Midlands | 34 | (21–46) | 4.12 | 1.98 | to | 6.25 | 2.86 | 2.05 | to | 3.68 |
West Midlands | 32 | (20–43) | 3.04 | 0.91 | to | 5.16 | 2.16 | 1.37 | to | 2.95 |
East of England | 34 | (23–45) | 5.10 | 2.19 | to | 8.01 | 3.34 | 2.41 | to | 4.27 |
South East | 32 | (19–43) | 2.26 | -0.76 | to | 5.28 | 1.87 | -0.38 | to | 4.12 |
South West | 27 | (11–40) | -2.21 | -4.34 | to | -0.08 | -2.39 | -3.19 | to | -1.59 |
Ethnicity, major groups 3 | ||||||||||
White | 33 | (21–43) | 0.00 | |||||||
Black | 30 | (21–42) | -0.60 | -4.95 | to | 3.75 | 0.57 | -2.97 | to | 4.11 |
Asian | 32 | (20–41) | -0.92 | -2.94 | to | 1.10 | -0.66 | -2.52 | to | 1.19 |
Mixed | 26 | (17–35) | -6.26 | -10.43 | to | -2.09 | -4.30 | -8.40 | to | -0.20 |
Other Ethnic Group | 30 | (18–40) | -2.94 | -6.44 | to | 0.55 | -2.15 | -4.99 | to | 0.68 |
Unknown | 34 | (22–44) | 0.47 | -0.39 | to | 1.33 | 0.27 | -0.80 | to | 1.34 |
Site | ||||||||||
Colon | 28 | (15–40) | 0.00 | |||||||
Rectosigmoid | 32 | (21–43) | 4.48 | 3.61 | to | 5.35 | 4.42 | 3.81 | to | 5.03 |
Rectum | 36 | (23–48) | 7.68 | 5.85 | to | 9.52 | 7.57 | 6.10 | to | 9.04 |
Stage | ||||||||||
A | 35 | (23–46) | 0.00 | |||||||
B | 28 | (15–41) | -5.83 | -6.25 | to | -5.41 | -4.12 | -4.46 | to | -3.77 |
Morphology | ||||||||||
Adenocarcinoma | 30 | (18–42) | 0.00 | |||||||
Mucinous adenocarcinoma | 28 | (14–40) | -2.45 | -3.26 | to | -1.64 | -0.84 | -1.44 | to | -0.25 |
Other | 32 | (18–43) | 1.00 | -0.16 | to | 2.16 | 1.18 | 0.23 | to | 2.12 |
Not otherwise specified | 28.5 | (8–39) | ||||||||
Grade | ||||||||||
G1 | 28 | (15–41) | 0.00 | |||||||
G2 | 30 | (18–42) | 1.81 | 0.67 | to | 2.94 | 1.16 | 0.27 | to | 2.06 |
G3 | 28 | (15–41) | 0.15 | -1.11 | to | 1.40 | 0.66 | -0.29 | to | 1.62 |
G4 | 20.5 | (6–33) | -7.82 | -12.76 | to | -2.88 | -6.45 | -11.02 | to | -1.88 |
Unknown | 29 | (13–43) | ||||||||
Deprivation quintile 4 | ||||||||||
1 - least deprived | 31 | (19–43) | 0.00 | |||||||
2 | 31 | (19–43) | -0.11 | -0.62 | to | 0.41 | 0.28 | -0.55 | to | 1.11 |
3 | 31 | (19–43) | -0.07 | -0.67 | to | 0.52 | 0.40 | -0.29 | to | 1.09 |
4 | 31 | (18–43) | -0.33 | -1.04 | to | 0.38 | 0.19 | -0.55 | to | 0.93 |
5 - most deprived | 30 | (17–42) | -0.52 | -1.84 | to | 0.80 | 0.21 | -0.55 | to | 0.98 |
Unknown | 21 | (9–35) | ||||||||
Cancer plan implementation period | ||||||||||
Prior to implementation | 24 | (12–37) | 0.00 | |||||||
Initialization | 29 | (16–42) | 4.23 | 3.09 | to | 5.37 | 4.83 | 3.56 | to | 6.10 |
Implementation | 33 | (22–44) | 7.06 | 4.10 | to | 10.01 | 8.02 | 5.53 | to | 10.51 |
1adjusted for all the other variables in the table except ethnicity.
2coefficient - represents the additional days between diagnosis and first resection for each category compared to the reference category.
3represents only data from 2005–2009.
4based on the income component of the 2007 Index of Multiple Deprivation.