Table 1.

Summary of key issues and corresponding HQLO references

Key issue	Author, year [reference number]
Development & interpretation of HRQoL outcomes	Bakas T et al., 2012 [2]; Johnston BC et al., 2013 [8]
Pediatric HRQoL measurement	Irwin DE et al., 2012 [10]; Rajmil L et al., 2013 [19]
Incorporation of HRQoL in economic evaluations	Jones C et al., 2012 [22]; Kim SH et al., 2012 [26]; Dakin H, 2013 [27]; Wilke S et al., 2012 [31]
Methodological issues and innovations in HRQoL measures
Measurement equivalence	Lix M et al., 2012 [42];
Selection bias	Hutchings A et al., 2012 [54]; Coste J et al., 2013 [55]
Evaluating change in health status	Wilson R et al., 2012 [58]; Turner N et al., 2013 [60]; Kuspinar A et al., 2013 [61]; Khadka J et al., 2012 [61]; Krabbe J et al., 2012 [63]